By discovering two genes responsible for early-onset Alzheimer’s, St. George-Hyslop and his team have made early diagnoses and treatment of the disease possible, often before brain damage occurs. They are currently taking some of the knowledge about the molecular mechanisms of the disease that were uncovered by their genetic studies, and using this information to develop novel diagnostics and treatments.
St. George-Hyslop has won one of Europe’s top health awards for his pioneering work on the roots of neurodegenerative diseases, including the BIAL Merit Award in Medical Sciences,
Among his honours and awards are the Francis A. McNaughton Prize from the Canadian Neurological Society and the Award for Medical Research from the Metropolitan Life Foundation and Distinguished Scientist in 2000. The Gold Medal in Medicine from the Royal College of Physicians of Canada in 1994 ,the Michael Smith Award from the Canadian Institutes of Health Research in 1997, and the Oon International Award in Preventive Medicine from the University of Cambridge. He is a member of the American Society for Clinical Investigation, a fellow of the Royal Society of Canada, and in 2007 was elected as a foreign member to the Institute of Medicine of the National Academy of Sciences and a fellow of the Royal Society of London.